Since the publication of the first edition of the Handbook of Human Immunology in 1997, major scientific achievements have elucidated our understanding of the complexities of the human immune system. This second edition compiles the major breakthroughs of the past decade including dramatic increases in the number of recognized clusters of differentiation on the surface of leukocytes and associated cells, establishment of an entire new chemokine and chemokine receptor nomenclature system, and discovery of more than 30 lymphokines. The text emphasizes clinically relevant immunological parameters, and clarifies the basic principles underlying immune system assays, as well as applications and interpretations of immune tests.

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